摘要 |
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are according to Formula 1501: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, PD, RA, RB, RC, L, M and Z are as described herein. |
申请人 |
IDENIX PHARMACEUTICALS, INC.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE DE MONTPELLIER |
发明人 |
MAYES, BENJAMIN ALEXANDER;MOUSSA, ADEL M.;STEWART, ALISTAIR JAMES;GOSSELIN, GILLES |