发明名称 |
GPC3-TARGETED THERAPEUTIC AGENT FOR ADMINISTRATION TO PATIENTS FOR WHOM GPC3-TARGETED THERAPEUTIC AGENT THERAPY IS EFFECTIVE |
摘要 |
The present invention discloses a method for determining the efficacy of GPC3-targeting drug therapy for cancer in a patient before the start of GPC3-targeting drug therapy or a patient or determining the continuation of GPC3-targeting drug therapy for a patient, including monitoring a concentration of free GPC3 in a biological sample isolated from the patient before the start of GPC3-targeting drug therapy and/or the patient treated with the GPC3-targeting drug therapy, wherein when the concentration of free GPC3 is a predetermined value, the efficacy of the GPC3-targeting drug therapy is determined or the continuation of the GPC3-targeting drug therapy is determined. The present invention also discloses a GPC3-targeting drug or a preparation which is to be further administered to a patient for which the efficacy of the GPC3-targeting drug therapy has been determined or the continuation of the GPC3-targeting drug therapy has been determined. |
申请公布号 |
EP2937697(A1) |
申请公布日期 |
2015.10.28 |
申请号 |
EP20130864465 |
申请日期 |
2013.12.24 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
OHTOMO, TOSHIHIKO;AMANO, JUN;NAKAMURA, MIKIKO |
分类号 |
G01N33/574;A61K39/395;A61K45/00;A61P1/16;A61P35/00;C07K16/30;G01N33/48;G01N33/53 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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