摘要 |
Provided are isolated TCRs, TCR-like molecules, and portions thereof that bind to phosphopeptide-HLA-A2 complexes. The isolated TCRs, TCR-like molecules, or portions are optionally soluble TCRs, TCR-like molecules, or portions. Also provided are isolated nucleic acids encoding the disclosed TCRs, TCR-like molecules, or portions; host cells that contain the disclosed TCRs, TCR-like molecules, or portions; pharmaceutical compositions that include the disclosed TCRs, TCR-like molecules, portions, nucleic acids, and/or T cells; kits; and methods of using the same. |
申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
ZARLING, ANGELA;ENGELHARD, VICTOR, H.;CUMMINGS, KARA, L.;OBENG, REBECCA, C. |