摘要 |
This invention provides compounds of formula I and subsets thereof: wherein T, J, R, R4, Rq, o, RA, and RB and subsets thereof are as described in the specification. The compounds are inhibitors of NAMPT and are thus useful for treating cancer, inflammatory conditions, or T-cell mediated autoimmune disease. |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
GIGSTAD, KENNETH M.;CARDIN, DAVID P.;HIRAYAMA, TAKAHARU;HIROSE, MASAAKI;HU, YONGBO;KAKEI, HIROYUKI;LEE, HONG MYUNG;MOTOYAJI, TAKASHI;NII, NORIYUKI;SHI, ZHAN;VYSKOCIL, STEPAN;WATANABE, HIROYUKI |