发明名称 |
APPLICATION OF SULFONAMIDES COMPOUND IN CHRONIC AIRWAY INFLAMMATORY DISEASE |
摘要 |
Provided is an application of a sulfonamides compound (i.e. the compound represented by general formula I) in chronic airway inflammatory diseases, particularly the use of Compound A or analogues thereof (Compound A1), for preparing a pharmaceutical composition treating diseases related to chronic airway inflammation. Compound A or analogues thereof of the present invention can reduce invasion and recruitment of inflammatory cells, particularly neutrophil granulocyte, and induce apoptosis of inflammatory cells, thus being used for chronic airway diseases such as bronchial asthma and COPD, and particularly for the treatment of chronic airway diseases where glucocorticoid has no effect. |
申请公布号 |
WO2015158299(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
WO2015CN76855 |
申请日期 |
2015.04.17 |
申请人 |
SHEN, HUAHAO;YING, SONGMIN;TIAN, BAOPING;CHEN, ZHIHUA;LI, WEN |
发明人 |
SHEN, HUAHAO;YING, SONGMIN;TIAN, BAOPING;CHEN, ZHIHUA;LI, WEN |
分类号 |
A61K31/63;A61K31/145;A61K31/495;A61P11/00 |
主分类号 |
A61K31/63 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|