| 摘要 |
A method of preventing, inhibiting, or treating cancer that includes contacting a cell with at least one compound of formula (Ia) or a pharmaceutically acceptable salt thereof:;;where:
R independently represents a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a —NR1R2 group, or a (C1-C3)alkoxy group;R′ is a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —NO2 group, a (C1-C3)alkoxy group, or a —NR1R2 group; andR1 and R2 are a hydrogen atom or a (C1-C3)alkyl group. |
| 主权项 |
1. A compound having the following formula or a pharmaceutically acceptable salt thereof:wherein:
R independently represent a hydrogen atom, a halogen atom, a —CN group, a hydroxyl group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a (C1-C3)fluoroalkoxy group, a—NO2 group, a —NR1R2 group, a (C1-C4)alkoxy group, a phenoxy group, or a (C1-C3)alkyl group optionally mono-substituted by a hydroxyl group,
R1 and R2 are independently a hydrogen atom or a (C1-C3)alkyl group, n is 1, 2, or 3, n′ is 1 or 2, R′ is a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a hydroxyl group, a—COOR1 group, a —NO2 group, a —NR1R2 group, a morpholinyl group, a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a (C1-C4)alkoxy group, or a —CN group, and
R″ is a hydrogen atom or a (C1-C4)alkyl group, with the proviso that: R and R are not simultaneously a hydrogen atom, when R′ is a hydrogen atom, R is not a —NO2 group or a —NH2 group, and when n is 2 and R′ is a hydrogen atom, R is not a COOC2H5 group or a chlorine atom. |
