| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula(I), or a pharmaceutically acceptable salt thereof, where Rand Rare independently selected from a group consisting of hydrogen, unsubstituted (C-C)alkyl, -CORand -COR; Rand Rcan also be cyclised to form a substituted or unsubstituted 4-, 5- or 6-member ring, selected from morpholine, piperidine, pyrrolidine, piperazine, azetidine, 4-methylpiperazine; Ris nitro or nitroso; Ris selected from a group consisting of ethynyl, propynyl or cyano; Ris selected from a group consisting of an unsubstituted (C-C)alkyl or unsubstituted aryl; Ris unsubstituted (C-C)alkyl. The invention also relates to methods of producing the compound of formula (I) (versions). The compounds of formula (I) are intended for preparing a pharmaceutical composition or a medicinal agent for treating a disease associated with a poly (ADP-ribose) polymerase (PARP) inhibitor, or for treating cancer, which contains an effective dose of a compound of formula (I) or a pharmaceutically acceptable salt thereof.EFFECT: benzamide derivatives intended for producing a medicinal agent for treating a disease associated with a poly (ADP-ribose) polymerase (PARP) inhibitor, or cancer.20 cl, 2 tbl, 37 ex |
