发明名称 antagonistas de piperidil acrilamida de ccr2
摘要 The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5 and X are as defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is uveitis, including acute, recurring or chronic uveitis. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
申请公布号 BRPI0914626(A2) 申请公布日期 2015.10.20
申请号 BR2009PI14626 申请日期 2009.06.19
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 CHAOZHONG CAI;ZHIHUA SUI
分类号 A61K31/33;A61P19/00;C07D209/14;C07D403/12 主分类号 A61K31/33
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