发明名称 Pancreatic cancer biomarker using the characteristics of pancreatic cancer stem cells, and use thereof
摘要 The present invention relates to a novel molecular marker for pancreatic cancer stem cells and pancreatic cancer, to a marker detection method, and to a screening method. The present invention is a marker discovered from the cell lines of pancreatic cancer, wherein the marker may detect pancreatic cancer, in particular early pancreatic cancer, through the detection of a pancreatic cancer stem cell marker. In addition, the marker of the present invention may enable an accurate diagnosis and prognosis analysis of pancreatic cancer.
申请公布号 US9164105(B2) 申请公布日期 2015.10.20
申请号 US201213979615 申请日期 2012.01.13
申请人 INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY 发明人 Song Si Young;Park Soo Been;Kim Sun A
分类号 A61K38/00;G01N33/68;G01N33/574;C12Q1/68;C12N15/113 主分类号 A61K38/00
代理机构 The PL Law Group, PLLC 代理人 The PL Law Group, PLLC
主权项 1. A method for treating GLRX3 (Glutaredoxin-3)-expressing pancreatic cancer in a mammalian subject in need thereof comprising, administering to the mammalian subject a therapeutically effective amount of an inhibitor against the GLRX3 (Glutaredoxin-3) activity or expression.
地址 Seoul KR