发明名称 |
Pancreatic cancer biomarker using the characteristics of pancreatic cancer stem cells, and use thereof |
摘要 |
The present invention relates to a novel molecular marker for pancreatic cancer stem cells and pancreatic cancer, to a marker detection method, and to a screening method. The present invention is a marker discovered from the cell lines of pancreatic cancer, wherein the marker may detect pancreatic cancer, in particular early pancreatic cancer, through the detection of a pancreatic cancer stem cell marker. In addition, the marker of the present invention may enable an accurate diagnosis and prognosis analysis of pancreatic cancer. |
申请公布号 |
US9164105(B2) |
申请公布日期 |
2015.10.20 |
申请号 |
US201213979615 |
申请日期 |
2012.01.13 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
Song Si Young;Park Soo Been;Kim Sun A |
分类号 |
A61K38/00;G01N33/68;G01N33/574;C12Q1/68;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
The PL Law Group, PLLC |
代理人 |
The PL Law Group, PLLC |
主权项 |
1. A method for treating GLRX3 (Glutaredoxin-3)-expressing pancreatic cancer in a mammalian subject in need thereof comprising, administering to the mammalian subject a therapeutically effective amount of an inhibitor against the GLRX3 (Glutaredoxin-3) activity or expression. |
地址 |
Seoul KR |