发明名称 |
Crystalline forms of an antiviral benzimidazole compound |
摘要 |
The invention relates to crystalline forms of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole, pharmaceutical compositions comprising the same, processes for preparing the same, and their use in medical therapy. |
申请公布号 |
US9163052(B2) |
申请公布日期 |
2015.10.20 |
申请号 |
US201113012924 |
申请日期 |
2011.01.25 |
申请人 |
GlaxoSmithKline LLC |
发明人 |
Glover Bobby Neal;Huang Lian-Feng;Lancaster Robert William;Long Stacey Todd;Rizzolio Michele Catherine;Schmitt Eric Allen;Sickles Barry Riddle |
分类号 |
A01N43/04;A61K31/70;C07H19/00;C07H19/04;C07H19/052;A61K31/4184;C07D405/04 |
主分类号 |
A01N43/04 |
代理机构 |
|
代理人 |
Thomas Robert Steve |
主权项 |
1. A pharmaceutical composition comprising a crystalline form of Form I 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1Hbenzimidazole having substantially the same X-ray powder diffraction pattern as FIG. 1, wherein said X-ray diffraction pattern is obtained with a diffractometer equipped with a diffracted beam curved graphite monochromator and utilizing copper Kα X-radiation, and at least one pharmaceutically acceptable carrier therefor; with the proviso that the pharmaceutical composition is not a solution of the active ingredient. |
地址 |
Wilmington DE US |