发明名称 METHOD OF OBTAINING NANOPARTICLES OF BORON NITRIDE FOR DELIVERY OF ANTI-TUMOUR MEDICATIONS
摘要 FIELD: medicine.SUBSTANCE: spherical nanoparticles of boron nitride with size 50-300 nm with developed external surface are synthesised by method of chemical precipitation from gas phase with application of reaction and transport gases, as well as powder mixtures, which consist of amorphous boron and reagent-oxidants, dispersion of agglomerates of obtained boron nitride nanoparticles by method of ultrasonic processing, saturation of boron nitride nanoparticles with anti-tumour medication by method of sorption and washing of nanoparticles in distilled water are carried out.EFFECT: method makes it possible to improve efficiency of anti-tumour chemotherapy due to increased activity of absorption of nanocontainers with anti-tumour medication by cells, prevention of toxicity of nanocontainers for cells.19 cl, 2 ex, 2 tbl
申请公布号 RU2565432(C1) 申请公布日期 2015.10.20
申请号 RU20140146689 申请日期 2014.11.20
申请人 FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "NATSIONAL'NYJ ISSLEDOVATEL'SKIJ TEKHNOLOGICHESKIJ UNIVERSITET "MISIS" 发明人 SHTANSKIJ DMITRIJ VLADIMIROVICH;KOVAL'SKIJ ANDREJ MIKHAJLOVICH;MATVEEV ANDREJ TROFIMOVICH;SUKHORUKOVA IRINA VIKTOROVNA;GLUSHANKOVA NATALIJA ALEKSANDROVNA;ZHITNJAK IRINA JUR'EVNA
分类号 A61K31/00;A61K9/51;A61K47/48;B82B3/00 主分类号 A61K31/00
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