| 摘要 |
Heterocylic group substituted 5-sulfamoyl benzoic acid and its salts (I; R1, R2 = H, C1-4 alkyl; when R1 is H, R2 is C2-5 alkoxymethyl, phenoxymethyl or phenylthiomethyl; R3 = H, C1-4 alkyls, C5-6 cycloalkyl, phenyl, benzyl; X = halogen, CF3, CCl3, C1-6 satd. or unsatd. alkyl or alkoxy, benzyl, OR4, SR4, SOR4, SO2R4 (R4 = Hal, OH, NH2, CF3, NO2); A= halogen, alkyl, aralkyl or side chain aryl group substituted C1-3 alkylene or singled bond; L = eliminatig group), useful as diuretic agent, were prepd. by treating sulfamoyl benzoic acid derivs. (II) with acid or base for eliminating HL group.
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