| 主权项 |
1. A compound of formula (I) or a salt thereof:wherein:
R1 and R2 are independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, phenyl, substituted phenyl, phenylalkyl, substituted phenylalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroarylalkyl, substituted heteroarylalkyl, heteroaryl or substituted heteroaryl; or R1 and R2 combine as to form a biradical selected from the group consisting of 3-hydroxy-pentane-1,5-diyl, 6-hydroxy-cycloheptane-1,4-diyl, propane-1,3-diyl, butane-1,4-diyl and pentane-1,5-diyl; R3 is H, alkyl, substituted alkyl, alkynyl or substituted alkynyl; R4 is H, alkyl, or substituted alkyl; R5 is alkyl, propargylic, substituted propargylic, homopropargylic, or substituted homopropargylic,
wherein at least one substituent selected from the group consisting of R1, R2, R3 and R5 is alkynyl or substituted alkynyl; R6 is H, alkyl, substituted alkyl or alkenyl; X is a bond, O or NR4; and, Y is N, CR6 or C; wherein:
if Y is N or CR6, then bond b1 is nil and:
(i) Z is H, bond b2 is a single bond, and A is CH; or,(ii) Z is nil, bond b2 is nil, and A is a single bond; and,if Y is C, then bond b1 is a single bond, and:
(i) Z is CH2, bond b2 is a single bond, and A is CH; or,(ii) Z is CH, bond b2 is a double bond, and A is C. |
