发明名称 Method of making an electrochemical sensor strip
摘要 A method of making an electrochemical sensor strip that includes: depositing a first electrode on a base; depositing a second electrode on the base; applying a first layer onto the first electrode; and applying a second layer onto the second electrode. The first layer includes an oxidoreductase and a mediator. The second layer includes a soluble redox species.
申请公布号 US9157111(B2) 申请公布日期 2015.10.13
申请号 US201414186991 申请日期 2014.02.21
申请人 Bayer Healthcare LLC 发明人 Wu Huan-Ping;Beer Greg P.;Blaschke Christina
分类号 G01N27/416;G01N27/327;C12Q1/00 主分类号 G01N27/416
代理机构 Nixon Peabody LLP 代理人 Nixon Peabody LLP
主权项 1. A method of making an electrochemical sensor strip, the method comprising: depositing a first electrode on a base; depositing a second electrode on the base; applying a first reagent layer onto the first electrode, the first reagent layer comprising an electroactive organic molecule and an oxidoreductase configured to facilitate a redox reaction of an analyte; and applying a second reagent layer onto the second electrode, the second reagent layer consisting essentially of a redox pair comprising a first soluble redox species and a second soluble redox species, the redox pair being selected from a group consisting of an organotransition metal complex, a transition metal coordination complex, and mixtures thereof, wherein the first soluble redox species is configured to undergo a redox reaction opposite that of the analyte, and wherein the molar ratio of the first soluble redox species to the second soluble redox species is greater than about 1.2:1 prior to use of the sensor strip in an analysis.
地址 Whippany NJ US