发明名称 |
Compuestos y métodos para inhibir el transporte de fosfato |
摘要 |
<p>Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.</p> |
申请公布号 |
ES2547890(T3) |
申请公布日期 |
2015.10.09 |
申请号 |
ES20110804369T |
申请日期 |
2011.07.07 |
申请人 |
ARDELYX, INC. |
发明人 |
LEWIS, JASON G.;JACOBS, JEFFREY W.;REICH, NICHOLAS;LEADBETTER, MICHAEL R.;BELL, NOAH;CHANG, HAN-TING;CHEN, TAO;NAVRE, MARC;CHARMOT, DOMINIQUE;CARRERAS, CHRISTOPHER;LABONTE, ERIC |
分类号 |
A61K31/506;A61K31/4965;C07D211/68;C07D401/00;C07D403/00;C07D413/00 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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