MAGNETIC NANOMETER TEMPERATURE IMAGING METHOD AND SYSTEM

摘要

Disclosed are a magnetic nanometer temperature imaging method: first, applying a constant DC magnetic field and an AC magnetic field simultaneously to the region of a magnetic nanoparticle sample, acquiring an AC magnetic intensity signal of the magnetic nanoparticles, and detecting each odd harmonic amplitude; then, replacing a constant DC gradient field with a combined DC magnetic field containing a gradient magnetic field, acquiring the AC magnetic intensity signal of the magnetic nanoparticles, and detecting each odd harmonic amplitude; calculating the difference between the two harmonic amplitudes; establishing a relation between the odd harmonic amplitude difference and the temperature using Taylor series expansion of a Langevin square function, and solving the relation to obtain an in vivo temperature; finally, changing the DC gradient field to the next position until the completion of temperature measurement in the whole one-dimensional space. The present invention applies different excitation fields to magnetic nanoparticles, thus transforming temperature imaging of the one-dimensional space to solve each point temperature in a small interval, further obtaining the one-dimensional temperature field precisely and rapidly without knowing the concentration of the magnetic nanoparticles.