发明名称 |
METHOD FOR TREATING HYPERGLYCEMIA WITH GLP-1 |
摘要 |
A method for treating hyperglycemia and/or diabetes in a subject is provided. In particular, the method is directed for the treatment of patients with type 2 diabetes mellitus who have a fasting blood glucose concentration greater than about 8 mM, wherein the patient is administered a formulation comprising a GLP-1 molecule and a diketopiperazine by pulmonary inhalation with a dry powder inhalation system. |
申请公布号 |
US2015283213(A1) |
申请公布日期 |
2015.10.08 |
申请号 |
US201514719920 |
申请日期 |
2015.05.22 |
申请人 |
MannKind Corporation |
发明人 |
Costello Donald;Richardson Peter;Baughman Robert A.;Marino Mark T. |
分类号 |
A61K38/26;A61K47/22;A61K9/00;A61K45/06 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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主权项 |
1. Use of a glucagon like peptide-1 (GLP-1) molecule in the manufacture of a medicament for treating hyperglycemia, wherein said medicament is administered to a subject having a fasting blood glucose concentration greater than about 7 mmol/L and said medicament comprises an inhalable dry powder formulation comprising a therapeutically effective amount of a GLP-1 molecule and a diketopiperazine. |
地址 |
Valencia CA US |