| 发明名称 |
INHIBITORS OF HISTONE DEMETHYLASES |
| 摘要 |
Compounds of the form in which Q is selected from -COOH -CH=NR12, -W, -CH2NHR13, -CH=0 and -CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds. |
| 申请公布号 |
CA2943824(A1) |
申请公布日期 |
2015.10.08 |
| 申请号 |
CA20152943824 |
申请日期 |
2015.03.30 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
LABELLE, MARC;BOESEN, THOMAS;ZHANG, RUI;MARTYR, CUTHBERT D.;SARASWAT, NEERJA |
| 分类号 |
C07D213/79;A61K31/395;A61K31/44;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4985;A61K31/501;A61K31/506;A61K31/551;C07D401/04;C07D401/12;C07D409/12;C07D417/12;C07D471/04;C07D487/04 |
主分类号 |
C07D213/79 |
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