发明名称 ANTI-FIBROTIC PYRIDINONES
摘要 This application relates to polycyclic compounds with a pyridinone or pyridinone derivative core including, substituted pyridinones, 5,6- and 6,6- bicyclic heterocycles and substituted pyridine-thiones. This application also discloses methods of preparing these polycyclic compounds, pharmaceutical compositions and medicaments comprising said compounds and methods to treat, prevent or diagnose diseases, disorders or conditions associated with fibrosis.
申请公布号 CA2943363(A1) 申请公布日期 2015.10.08
申请号 CA20152943363 申请日期 2015.03.31
申请人 INTERMUNE, INC. 发明人 RAMPHAL, JOHNNIE Y.;BUCKMAN, BRAD OWEN;EMAYAN, KUMARASWAMY;NICHOLAS, JOHN BEAMOND;SEIWERT, SCOTT D.
分类号 C07D471/04;A61K31/395;A61K31/437;A61K31/4985;A61P11/00;A61P13/12;C07C49/753;C07C211/52;C07D205/08;C07D207/267;C07D209/34;C07D209/38;C07D209/48;C07D211/76;C07D213/46;C07D213/70;C07D221/04;C07D223/10;C07D401/00;C07D405/00;C07D409/00;C07D413/00;C07D417/00;C07D491/048;C07D495/04;C07D498/04;C07D513/04;C07D519/00 主分类号 C07D471/04
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