发明名称 |
METHOD FOR PRODUCING REDUCED COENZYME Q10 |
摘要 |
Provided is a production method of Form I crystal of reduced coenzyme Q10 or a crystalline solid thereof, which is substantially free of Form II crystal, including a step of holding a solution containing reduced coenzyme Q10 at a temperature exceeding 47° C. for at least 60 minutes, and a step of crystallization thereafter. |
申请公布号 |
US2015284311(A1) |
申请公布日期 |
2015.10.08 |
申请号 |
US201314397363 |
申请日期 |
2013.04.26 |
申请人 |
KANEKA CORPORATION |
发明人 |
Kawachi Hideo;Kitamura Shiro;Ueda Yasuyoshi |
分类号 |
C07C46/10 |
主分类号 |
C07C46/10 |
代理机构 |
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代理人 |
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主权项 |
1: A method of producing Form I crystal of reduced coenzyme Q10 or a crystalline solid thereof, comprising:
holding a solution containing comprising reduced coenzyme Q10 at a temperature of from 55° C. to 75° C. for at least 60 minutes; and crystallizing the reduced coenzyme Q10 to produce a Form I crystal of the reduced coenzyme Q10 or a crystalline solid thereof, which is substantially free of Form II crystal, wherein the crystallizing comprises cooling the solution. |
地址 |
Osaka-shi, Osaka JP |