Glucose alteration methods

摘要

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

主权项

1. A method of altering glucose levels, the method comprising:
inserting a cryoablation catheter into a vasculature of a subject, wherein said cryoablation catheter comprises a distal end, advancing the distal end of the cryoablation catheter to a location within a portion of a common hepatic artery of the vasculature; and ablating one or more nerves surrounding the portion of the common hepatic artery using the cryoablation catheter to decrease a glucose level within the subject.