Substituted imidazopyridines and the use thereof

摘要

The present application relates to novel substituted imidazopyridazines having the following formula (I):;
to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.

主权项

1. A compound of formula (I)in which
R1 is 2-fluorobenzyl, A is C—N(R2)—C(═O)—R3,
whereR2 is hydrogen, methyl, ethyl or 2,2,2-trifluoroethyl,R3 is (C1-C4)-alkoxy, cyclobutoxy or cyclopentoxy,
in which (C1-C4)-alkoxy may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine and trifluoromethyl,orR2 and R3 together with the atoms to which they are attached form a pyrrolidinonyl or oxazolidinonyl ring, or a pharmaceutically acceptable salt thereof.