主权项 |
1. A compound of formula (I)wherein
R1 is
hydrogen,(C1-C6)alkyl,(C3-C7)cycloalkyl,(C3-C7)cycloalkyl-(C1-C6)alkyl-,Rb—O—Ra— where Rb is (C1-C6)alkyl or (C3-C7)cycloalkyl and Ra is (C1-C6)alkyl,Rd-O—C(O)—O-Rc- where Rd is (C1-C6)alkyl or (C3-C7)cycloalkyl, and Rc is (C1-C6)alkyl, orRf—C(O)—O—Re— where Re is (C1-C6)alkyl and Rf is (C1-C6)alkyl; R2 is
halogen,—OH,—CN,(C1-C6)alkyl or —O—(C1-C6)alkyl in which each (C1-C6)alkyl is non-substituted or substituted by one or more halogen identical to or different from one another, orRg-O—Rh—O—, in which Rg is (C1-C6)alkyl and Rh is (C1-C6)alkyl; R2′ is hydrogen or (C1-C6)alkyl; R3 is wherein R4 and R5 are, independently of one another, (C1-C6) alkyl or (C3-C7)cycloalkyl, or R4 and R5, when taken together with the nitrogen atom to which they are attached, form a 3 to 7 membered heterocycloalkyl comprising from 1 to 2 heteroatoms chosen from nitrogen, oxygen and sulphur, said heterocycloalkyl being non-substituted or substituted by one or more groups independently selected from halogen, (C1-C6)alkyl, (C1-C6)alkoxy, —CF3 and —OCF3; and R6 is halogen, hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy or —CN; or an enantiomer, diastereoisomer or mixture thereof, or pharmaceutically acceptable salt thereof. |