发明名称 |
RET INHIBITOR |
摘要 |
A compound represented by the following general formula (I) [the symbol in the formula are as defined in the description], a salt thereof, or the like is a RET inhibitor or RET tyrosine kinase inhibitor that can be used as an agent for the prevention or treatment of disorders including cancers and cancer metastasis having mutations in RET.; |
申请公布号 |
US2015272958(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
US201314429834 |
申请日期 |
2013.09.24 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
Kodama Tatsushi;Sakamoto Hiroshi;Tsukaguchi Toshiyuki |
分类号 |
A61K31/5377;G01N33/573;C12Q1/68 |
主分类号 |
A61K31/5377 |
代理机构 |
|
代理人 |
|
主权项 |
1. A therapeutic and/or prophylactic agent for a tumor with a mutation in RET and for metastasis of the tumor, which comprises a compound represented by formula (I), a salt thereof or a solvate thereof as an active ingredient:wherein R1 is a C1-6 alkyl group. |
地址 |
Kita-ku, Tokyo JP |