发明名称 RET INHIBITOR
摘要 A compound represented by the following general formula (I) [the symbol in the formula are as defined in the description], a salt thereof, or the like is a RET inhibitor or RET tyrosine kinase inhibitor that can be used as an agent for the prevention or treatment of disorders including cancers and cancer metastasis having mutations in RET.;
申请公布号 US2015272958(A1) 申请公布日期 2015.10.01
申请号 US201314429834 申请日期 2013.09.24
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 Kodama Tatsushi;Sakamoto Hiroshi;Tsukaguchi Toshiyuki
分类号 A61K31/5377;G01N33/573;C12Q1/68 主分类号 A61K31/5377
代理机构 代理人
主权项 1. A therapeutic and/or prophylactic agent for a tumor with a mutation in RET and for metastasis of the tumor, which comprises a compound represented by formula (I), a salt thereof or a solvate thereof as an active ingredient:wherein R1 is a C1-6 alkyl group.
地址 Kita-ku, Tokyo JP