| 发明名称 |
METHOD OF MANUFACTURING 1,4-BUTANEDIOL AND MICROBE |
| 摘要 |
A method of manufacturing 1,4-butanediol, using a microbe and/or a culture thereof, by an enzyme reaction system that uses acetoacetyl-CoA reductase and enoyl-CoA hydratase, via acetoacetyl-CoA, 3-hydroxybutyryl-CoA and crotonyl-CoA in this order, wherein each of the acetoacetyl-CoA reductase and the enoyl-CoA hydratase is specific to a stereoisomer of 3-hydroxybutyryl-CoA. |
| 申请公布号 |
US2015275236(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
US201314438292 |
申请日期 |
2013.09.13 |
| 申请人 |
SHOWA DENKO K.K. |
发明人 |
Aoki Hirobumi;Kokido Yuzuru;Hashimoto Yoko;Yoneda Tadashi |
| 分类号 |
C12P7/18;C12N9/02;C12N9/90;C12N9/04;C12N9/88 |
主分类号 |
C12P7/18 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of manufacturing 1,4-butanediol, using a microbe and/or a culture thereof, by an enzyme reaction system that uses acetoacetyl-CoA reductase and enoyl-CoA hydratase, via acetoacetyl-CoA, 3-hydroxybutyryl-CoA and crotonyl-CoA in this order,
wherein each of the acetoacetyl-CoA reductase and the enoyl-CoA hydratase is specific to a stereoisomer of 3-hydroxybutyryl-CoA. |
| 地址 |
Tokyo JP |
