发明名称 ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES
摘要 Compounds having the following formula (I): or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
申请公布号 EP2922841(A1) 申请公布日期 2015.09.30
申请号 EP20130795911 申请日期 2013.11.07
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 MOSLIN, RYAN M.;LIN, SHUQUN;WEINSTEIN, DAVID S.;WROBLESKI, STEPHEN T.;ZHANG, YANLEI;TOKARSKI, JOHN S.;MERTZMAN, MICHAEL E
分类号 C07D401/14;A61K31/444;A61P29/00;A61P35/00;A61P37/00;C07D401/12;C07D405/14;C07D413/14;C07D417/14;C07D471/04 主分类号 C07D401/14
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