发明名称 Therapeutically active substances and method of obtaining such substances
摘要 Active substances, specific for the decomposition of foreign proteins of diseased tissues of the body, are obtained by growing proteolytic micro-organisms on proteins of the types to be decomposed and extracting, from the products of the growths, liquids which contain the active substances. The process is described by reference to the treatment of carcinoma tissue and the lenses of pigs which become cataractous shortly after their removal and are therefore to be regarded as equivalent to diseased living tissue. The tissue in question is placed in a liquid culture medium, e.g. NaCl solution and inoculated with a culture of proteolytic bacteria, e.g. B. subtilis, B. histrolyticus, B. prodigiosis, B. proteus. After a sufficient time, e.g. 24 hours and upwards, the active preparation is separated by centrifuging and filtration. The preparation may be adjusted by acidification or alkalinization. Treatment of sarcomatous and tuberculous tissue is also referred to.
申请公布号 GB466029(A) 申请公布日期 1937.05.19
申请号 GB19350032080 申请日期 1935.11.19
申请人 HENDRY CAMERON CONNELL 发明人
分类号 A61K35/74 主分类号 A61K35/74
代理机构 代理人
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