CAPTURE AND RANDOM AMPLIFICATION PROTOCOL FOR IDENTIFICATION AND MONITORING OF MICROBIAL DIVERSITY

摘要

Sequence capture and random amplification are used to generate a population of polynucleotides that reflect the sequence diversity of a starting microbial population. The CAPRA population is used in hybridization reactions for the assessment of diversity and for the quantitation of particular members in the starting population. The polynucleotide population can also be sequenced, and/or cloned for evaluation of sequence diversity, generation of probes, generation of microarrays comprising such sequences, and the like.