发明名称 Gsk-3 inhibitors isolated from marine organisms
摘要 The present invention provides the use of a compound of formula (I); wherein: n is 0, 1, 2, or 3, the bonds shown with the dashed lines are saturated, or unsaturated with one or more double bonds; R, and R'are independently selected from hydrogen, alkyl, aryl, -OH, -OR'' -SH, -SR''-NH, -NHR'', -O, -NH, -NR''; R'' is independently selected from alkyl, aryl, in the preparation of a medicament for the treatment of a disease requiring a GSK-3 inhibitor. Also provided is a compound of formula (II); wherein n is 0, 1, 2, or 3 the bonds shown with the dashed lines are saturated, or unsaturated with one or more double bonds. Also provided are methods of treating chronic neurodegenerative conditions.
申请公布号 US2007088080(A1) 申请公布日期 2007.04.19
申请号 US20040596188 申请日期 2004.12.02
申请人 NEUROPHARMA, S.A. 发明人 GORDILLO DIANA A.;DIAZ ISABEL D.;MARTINEZ-GIL ANA;DEL PLIEGO GEMA P.;HUERTA ANA F.;PUERTO MA JOSE P.;APARICIO ESTER M.;NAVARRO DARIO P.;PADILLA MIGUEL M.
分类号 A61K31/365;C07D307/60;C07D307/62;C07D405/02;C07D407/06 主分类号 A61K31/365
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