发明名称 Combination of VEGF receptor tyrosine kinase inhibitors for treatment of cancer
摘要 The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with ZD1839; to a pharmaceutical composition comprising ZD6474 and ZD1839; to a combination product comprising ZD6474 and ZD1839 for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and ZD1839; to the use of ZD6474 and ZD1839 in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.
申请公布号 ZA200501061(B) 申请公布日期 2007.01.31
申请号 ZA20050001061 申请日期 2005.02.04
申请人 ASTRAZENECA AB. 发明人 WEDGE, STEPHEN ROBERT
分类号 A61K;A61K31/517;A61K45/06;A61P;A61P9/00;A61P35/00 主分类号 A61K
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