Neuronally expressed stem cell factor modulates angiogenesis and neural stem cell migration to areas of brain injury

摘要

The present invention relates to methods of promoting or inhibiting angiogenesis in humans comprising administering to a human in need thereof an effective amount of Stem Cell Factor or a modulator of Stem Cell Factor or an agonist or antagonist of c-Kit and methods of inducing migration of a neural stem or progenitor cell to a site of neurological injury in the central nervous system of a subject.