发明名称 |
POLYMER-CERAMIC-HYDROGEL COMPOSITE SCAFFOLD FOR OSTEOCHONDRAL REPAIR |
摘要 |
This invention pertains to materials and methods relating to the biological fixation of one tissue type to another different tissue type, i.e., the fixation of cartilage to bone. A scaffold apparatus for osteochondral tissue engineering is described. The apparatus comprises regions of varying matrices which provide a functional interface between multiple tissue types. Further, a method for preparing the scaffold apparatus is provided. Methods for treating osteochondral tissue injury and cartilage degeneration using the scaffold apparatus are also described. In addition, a method for evaluating cellmediated and scaffold-related parameters of development and maintenance of multiple tissue zones in vitro is described.
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申请公布号 |
WO2005089127(A8) |
申请公布日期 |
2006.10.05 |
申请号 |
WO2005US07010 |
申请日期 |
2005.03.04 |
申请人 |
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发明人 |
LU, HELEN, H.;JIANG, JIE;HUNG, CLARK, T.;GUO, X., EDWARD;ATESHIAN, GERARD |
分类号 |
A61F2/00;A61F2/02;A61F2/28;A61F2/30;A61K35/12;A61L27/38;C12N5/071;C12N5/077 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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