发明名称 |
CELL CULTURE WITH NM23, CELL CULTURE MEDIA COMPRISING NM23 AND THERAPEUTIC USE OF CELLS CULTURED IN THE PRESENCE OF NM23. |
摘要 |
<p>The protein NM23 is disclosed as an agent for the maintenance of undifferentiated biological cells in culture. The NM23 protein may act as a survival factor for such cultured cells, or to prevent the differentiation and maturation of the cultured cells. The use of NM23 protein is applicable to culture of stem and/or progenitor cells, and particularly to such cells cultured and adapted for therapeutic use. The invention provides methods, media and media supplements for use in the culture of biological cells, and further provides methods of preparing biological cells for therapeutic use, as well as methods of therapy utilising biological cells and medicaments comprising biological cells adapted for therapeutic use.</p> |
申请公布号 |
WO2005056780(A8) |
申请公布日期 |
2006.10.05 |
申请号 |
WO2004GB04826 |
申请日期 |
2004.11.16 |
申请人 |
THE UNIVERSITY OF BIRMINGHAM;BUNCE, CHRISTOPHER, MARTIN |
发明人 |
BUNCE, CHRISTOPHER, MARTIN |
分类号 |
A61K35/12;C12N5/00;C12N5/0789 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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