| 发明名称 |
COMPOSITIONS FOR THE DELIVERY OF RNA INTERFERENCE MOLECULES AND METHODS FOR THEIR USE |
| 摘要 |
The present invention provides compositions for the treatment and/or prevention of a disorder in a mammal by means of RNA interference, together with methods for the use of such compositions. The inventive compositions comprise a small interfering nucleic acid molecule (siNA) that suppresses expression of a target gene within the target cell, or a genetic construct that expresses such a siNA, wherein the target gene is CXCR4, SDF-1 and/or HCLCA1. |
| 申请公布号 |
WO2006091112(A1) |
申请公布日期 |
2006.08.31 |
| 申请号 |
WO2006NZ00026 |
申请日期 |
2006.02.22 |
| 申请人 |
TED GENESIS REASEARCH AND DEVELOPMENT CORPORATIONLIMI;MUNRO, GRANT;ABERNETHY, NEVIN;HAVUKKALA, ILKKA J.;REID, GLEN |
发明人 |
MUNRO, GRANT;ABERNETHY, NEVIN;HAVUKKALA, ILKKA J.;REID, GLEN |
| 分类号 |
A61K31/713;A61K48/00;A61P11/00;A61P11/06;A61P11/12;A61P31/18;A61P35/00;C12N15/113;C12N15/12 |
主分类号 |
A61K31/713 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
