发明名称 Conjugates of ligand linker and cytotoxic agent and related composition and methods of use
摘要 A conjugate comprising a ligand, a linker, and a cytotoxic agent, in which the linker is FALA, VLALA, ALAL, ALALA, ChaLALA, ChaChaLAL, NalChaLAL or NalLALA; a composition thereof; a method of delivering a cytotoxic agent in a cell-specific manner; and a method of treating cancer in a mammal.
申请公布号 US2005171014(A1) 申请公布日期 2005.08.04
申请号 US20040505239 申请日期 2004.10.12
申请人 GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH 发明人 TARASOVA NADYA I.;MICHEJDA CHRISTOPHER J.;DYBA MARCIN;COHRAN CAROLYN
分类号 A61K38/00;A61K47/48;C07K5/02;C07K5/065;C07K7/02;C07K7/06;C07K14/595;(IPC1-7):A61K38/17;C07K14/655 主分类号 A61K38/00
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