发明名称 |
New conjugates associating, by covalent bond, an enzyme with an antibody, and medicinal associations using the said conjugates |
摘要 |
The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms. The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.
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申请公布号 |
US4762707(A) |
申请公布日期 |
1988.08.09 |
申请号 |
US19850736334 |
申请日期 |
1985.05.21 |
申请人 |
SANOFI (SOCIETE ANONYME) |
发明人 |
JANSEN, FRANZ;GROS, PIERRE |
分类号 |
A61K39/395;A61K38/36;A61K38/46;A61K47/48;C12N11/06;(IPC1-7):A61K39/395;A61K39/44;A61K37/48;C12N11/02 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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