| 摘要 |
Compounds of general formula (I), wherein R1 is se-lected from phenyl, pyridinyl, thiophenyl, furanyl and imidazolyl; each phenyl ring and heteroaromatic ring otpionally and independently be-ing further substituted by 1,2 or 3 substituents selected from straight a nd branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo; are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain.
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