发明名称 Heterocyclic compounds and thrombopoietin receptor activators
摘要 A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C2-14 aryl group, L1 is a bond, CR10R11, an oxygen atom, a sulfur atom or NR12, X is OR13, SR13 or NR14NR15, R2 is a hydrogen atom, a formyl group, a C1-10 alkyl group or the like, L2 is a bond or the like, L3 is a bond, CR17R18, an oxygen atom, a sulfur atom or NR19, L4 is a bond, CR20R21, an oxygen atom, a sulfur atom or NR22, Y is an oxygen atom, a sulfur atom or NR23, and R3 is a C2-14 aryl group, a tautomer, prodrug or is pharmaceutically acceptable salt of the compound or a solvate thereof.
申请公布号 US7576115(B2) 申请公布日期 2009.08.18
申请号 US20070837659 申请日期 2007.08.13
申请人 NISSAN CHEMICAL INDUSTRIES, LTD. 发明人 OWADA SHINGO;IWAMOTO SHUNSUKE;YANAGIHARA KAZUFUMI;MIYAJI KATSUAKI;NAKAMURA TAKANORI;ISHIWATA NORIHISA;HIROKAWA YUTAKA
分类号 A61K31/415;A61P7/00;A61P35/00;C07D231/10;C07D231/18;C07D333/32;C07D333/38;C07D403/12;C07D409/12 主分类号 A61K31/415
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