摘要 |
PROBLEM TO BE SOLVED: To provide a new imaging agent utilizing an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. SOLUTION: This tumor-imaging agent includes a labeled compound obtained by radioactive-labeling a specific quinazoline derivative represented by the compound: [(3-ethynyl-phenyl)-quinazolin-4-ylamine]. The specific quinazoline derivative exhibits an inhibitory activity of the EGFR tyrosine kinase, and the tumor-imaging agent by using the same has a >1 accumulation ratio to a tumor tissue. COPYRIGHT: (C)2009,JPO&INPIT
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