发明名称 |
COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF WOUNDS |
摘要 |
<p>The present invention provides a topical composition comprising (i) an amount of an AP-1 signaling inhibitor sufficient to reduce, delay or prevent apoptosis and/or necrosis induced by dermal wounding and/or to induce and/or enhance proliferation of a cell; and (ii) a suitable carrier or excipient e.g., a topical carrier or excipient or other carrier or excipient for dermal application. For example, the AP-1 signaling inhibitor is a peptide analog comprising the sequence set forth in SEQ ID NO: 104. The present invention also provides a method of treating a dermal wound comprising topically administering said topical composition to a subject suffering from a dermal wound.</p> |
申请公布号 |
EP2079526(A1) |
申请公布日期 |
2009.07.22 |
申请号 |
EP20070701453 |
申请日期 |
2007.02.06 |
申请人 |
PHYLOGICA LIMITED;THE MCCOMB FOUNDATION, INC. |
发明人 |
FEAR, MARK;WATT, PAUL;HOPKINS, RICHARD;MILECH, NADIA |
分类号 |
C07K14/195;A61K38/10;A61K38/16;A61P25/06;A61P25/16;A61P25/28;C07K7/08;C07K14/16;C07K19/00;C12N15/18;C12N15/31 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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