发明名称 |
SYSTEM FOR OSMOTIC DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS |
摘要 |
<p>An osmotic system for delivering a pharmaceutically active agent which comprises a core portion, a layer portion enclosing the core portion, and a semipermeable wall portion enclosing the core portion and the layer portion. The core portion includes the pharmaceutically active agent at a first concentration. The pharmaceutically active agent is present in the layer portion at a second concentration. The second concentration is greater than the first concentration. Such a system provides for the osmotic release of the pharmaceutically active agent in release profile other than a zero order release profile, and wherein the release profile is similar to or approaches or reaches a first order release profile.</p> |
申请公布号 |
EP1392241(B1) |
申请公布日期 |
2009.07.22 |
申请号 |
EP20020731962 |
申请日期 |
2002.05.30 |
申请人 |
SUPERNUS PHARMACEUTICALS, INC. |
发明人 |
BURNSIDE, BETH, A.;FLANNER, HENRY, H.;MCKNIGHT, LISA, C. |
分类号 |
A61K9/20;A61K9/00;A61K9/22;A61K9/24;A61K9/28;A61K9/30;A61K9/32;A61K9/36;A61K31/137;A61K38/00;A61K47/38;A61P25/26;A61P27/16;A61P31/04;A61P31/12;A61P31/16;A61P31/18;A61P35/00;A61P37/04;A61P37/08 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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