Modular antigen transporter molecules (MAT molecules) for modulating immune reactions, associated constructs, methods and uses

摘要

Modular antigen transporter molecules (MAT molecules), which are used as vaccines and for the treatment of allergies, include three modules: a translocation module which brings about transport of the MAT molecule into the interior of the cell; a targeting module which directs the MAT molecule to intracellular organelles involved in antigen processing and loading; and an antigen module which contains an allergen.