PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
摘要
The present invention provides a process for preparing highly pure montelukast and salts thereof by reacting the side-chain precursor 1-(mercaptomethyl)-cyclopropaneacetic acid with 2-(2-(3S)-(3-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(methanesulfonyloxypropyl)phenyl-2-propanol in a solvent mixture containing a base.
申请公布号
WO2007096889(A3)
申请公布日期
2009.04.16
申请号
WO2007IL00251
申请日期
2007.02.27
申请人
CHEMAGIS LTD.;BRAND, MICHAEL;SHOOKRUN, MOTY;ARAD, ODED;KASPI, JOSEPH
发明人
BRAND, MICHAEL;SHOOKRUN, MOTY;ARAD, ODED;KASPI, JOSEPH