发明名称 PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
摘要 The present invention provides a process for preparing highly pure montelukast and salts thereof by reacting the side-chain precursor 1-(mercaptomethyl)-cyclopropaneacetic acid with 2-(2-(3S)-(3-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(methanesulfonyloxypropyl)phenyl-2-propanol in a solvent mixture containing a base.
申请公布号 WO2007096889(A3) 申请公布日期 2009.04.16
申请号 WO2007IL00251 申请日期 2007.02.27
申请人 CHEMAGIS LTD.;BRAND, MICHAEL;SHOOKRUN, MOTY;ARAD, ODED;KASPI, JOSEPH 发明人 BRAND, MICHAEL;SHOOKRUN, MOTY;ARAD, ODED;KASPI, JOSEPH
分类号 C07D215/16;A61K31/47 主分类号 C07D215/16
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