The invention provides a method for the treatment of Lymphangioleiomyomatosis (LAM) in the human subject in need thereof. The method comprises administering to the subject an effective amount of doxycycline or a salt thereof. The invention further provides a method for monitoring the efficacy of treatment. Treatment efficacy is monitored by measuring MMP levels. Reduction in MMP levels indicates that the treatment is effective.
申请公布号
WO2006124961(A3)
申请公布日期
2009.04.16
申请号
WO2006US19020
申请日期
2006.05.16
申请人
CHILDREN'S MEDICAL CENTER CORPORATION;FOLKMAN, JUDAH;MOSES, MARSHA, A.