FELINE INFECTIOUS PERITONITIS (FIP) AND SYSTEMIC MULTI-ORGAN CORONAVIRUS BIOMARKERS AND SCREENING METHODS

摘要

Methods for screening for FIP infection or other multi-organ coronaviruses are disclosed, as well as isolated antibodies and kits useful for performing such methods. Biomarkers for multi-organ coronavirus infections include soluble enolase; antibodies to enolase; and circulating immune complexes that contain enolase. The methods find application in diagnosis, treatment, vaccine-development, and selection or breeding for disease-resistance.