发明名称 VASCULOSTATIC AGENTS AND METHODS OF APPLICATION THEREOF
摘要 FIELD: chemistry. ^ SUBSTANCE: invention refers to new compounds of formula (I): , where: each R0 independently stands for -H, -COOH, -OR', -SO3H, where R' stands for -H, lower alkyl, or, if x=2, both Ro are taken together to form 1,3-dioxolyl ring, or each Ro independently represents lower alkyl, each R1 and R2, is independent standing for hydrogen, G stands for (CR"2)p where R" stands for -H or acetamido and where p is equal to 0-3, Ar stands for aryl or 6-merous heteroaryl with one N atom as heteroatom, and each x and y is independent, equal to 1-4. ^ EFFECT: compounds I can be used in pharmaceutical compositions with vasculostatic activity, reducing overflow from blood vessels, for treating cancer, a heart attack and similar. ^ 72 cl, 7 ex, 2 tbl
申请公布号 RU2351586(C2) 申请公布日期 2009.04.10
申请号 RU20050113978 申请日期 2003.10.02
申请人 TARGEDZHEN, INK. 发明人 VRAZIDLO VOL'FGANG;DUKAS DZHON;ROJSTON IVOR;NORONKHA GLENN;KHUD DZHON D.;DNEPROVSKAJA ELENA;GUN SJAN'SHAN;SPLITGERBER JUT;CHZHAO NINNIN
分类号 C07D209/14;A61K31/404;A61K31/405;A61K31/525;A61K31/724;A61P9/10;A61P35/00;C07D209/02;C07D209/04;C07D209/48;C07D239/88;C07D239/90;C07D239/95;C07D241/42;C07D253/10;C07D401/12;C07D403/12;C07D405/04;C07D405/12;C07D471/04;C07D475/06;C07D487/04;C07D519/00 主分类号 C07D209/14
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