| 发明名称 |
TETRAHYDRO ISOQUINOLINE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF |
| 摘要 |
<p>A kind of tetrahydro isoquinoline derivatives (I), their preparation methods, medicine compositions and medicinal uses thereof, especially their uses as º-opioid receptor excitant in pain relieving, which belongs to the medicine chemistry. The substituents R 1 , R 2 , R 3 , R 4 of general formula (I) are defined as the description.</p> |
| 申请公布号 |
EP2045243(A1) |
申请公布日期 |
2009.04.08 |
| 申请号 |
EP20070764022 |
申请日期 |
2007.07.10 |
| 申请人 |
CHINA PHARMACEUTICAL UNIVERSITY;SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES;YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. |
发明人 |
XU, YUNGEN;LIU, JINGGEN;GUO, TING;WANG, DECHUAN;SUN, TIANJIANG;LU, HONGGUO |
| 分类号 |
C07D217/06;A61K31/472;A61K31/4725;A61P9/12;A61P25/04;A61P25/20;A61P25/36;A61P29/00;A61P31/18;C07D401/06;C07D403/06;C07D471/10 |
主分类号 |
C07D217/06 |
| 代理机构 |
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