发明名称 COMBINATIONS OF AN ANTI-HER2 ANTIBODY-DRUG CONJUGATE AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE
摘要 Combinations of the antibody-drug conjugate trastuzumab-MCC-DM 1 and pertuzumab, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by HER2 and KDR (VEGFR receptor 1). Methods of using such combinations for in vitro , in situ , and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 KR20100129318(A) 申请公布日期 2010.12.08
申请号 KR20107023080 申请日期 2009.03.10
申请人 GENENTECH, INC. 发明人 BERRY LEANNE;PHILLIPS GAIL LEWIS;SLIWKOWSKI MARK X.
分类号 A61K39/395;A61K31/337;A61K31/517;A61P35/00 主分类号 A61K39/395
代理机构 代理人
主权项
地址