发明名称 |
Drug-polymer conjugates coupled to a peptidic carrier |
摘要 |
Monodisperse macromolecular conjugate compositions of a peptidic carrier irreversibly or reversibly conjugated with one or more effectors and one or more therapeutic agents, wherein at least one effector or therapeutic agent is attached to a pendant reactive group on said peptidic carrier via a water-soluble polymer. Monodispersity is obtained through the use of orthogonal and separate conjugation reactions.
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申请公布号 |
US7846893(B2) |
申请公布日期 |
2010.12.07 |
申请号 |
US20060816317 |
申请日期 |
2006.02.16 |
申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
SINKO PATRICK J.;STEIN STANLEY;GUNASEELAN SIMI;POOYAN SHAHRIAR;WAN LI;ZHANG XIAOPING |
分类号 |
A61K38/00;A01N25/34;A61K38/06;A61K38/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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