发明名称 POLYMER DERIVATIVE OF CYTIDINE ANTIMETABOLITE
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to a polymer derivative of cytidine antimetabolite of formula (1) which can be used as an antineoplastic drug: (1), where R is hydrogen or alkyl; A is hydrogen, acyl or alkoxycarbonyl; m is within 3 to 200; n is within 5 to 2000; X is a residue of cytidine antimetabolite, hydroxyl or a hydrophobic substitute, and X means a residue of cytidine antimetabolite in amount 3-100 % m, hydroxyl in amount 0-95 % m and the hydrophobic substitute in amount 0-80 % m. ^ EFFECT: preparation of new antineoplastic compounds. ^ 8 cl, 5 ex, 4 tbl
申请公布号 RU2404980(C2) 申请公布日期 2010.11.27
申请号 RU20070145718 申请日期 2006.04.27
申请人 NIPPON KAJAKU KABUSIKI KAJSJA 发明人 MASUDA AKIRA;ONDA TAKESI;MASIBA KHIROKO;JAMAMOTO KEJITIROU;TAKASIO KAZUTOSI
分类号 A61K31/51;A61K38/00;A61P35/00;C07D405/04;C08G65/48 主分类号 A61K31/51
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